Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.98 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409727 | 0.99 | PGR (1.00) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11903473 | 0.85 | PGR (0.72) | PGR | |
| SCHEMBL4104125 | 0.82 | PGR (0.71) | PGR | |
| SCHEMBL4104128 | 0.82 | PGR (0.71) | PGR | |
| SCHEMBL3422468 | 0.81 | PGR (0.70) | PGR | |
| SCHEMBL4534292 | 0.81 | PGR (0.70) | PGR | |
| SCHEMBL1223269 | 0.81 | PGR (0.67) | PGR | |
| SCHEMBL5226194 | 0.79 | PGR (1.00) | PGR | |
| SCHEMBL3523720 | 0.78 | PGR (1.00) | PGR | |
| SCHEMBL5225371 | 0.76 | PGR (1.00) | PGRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173433-B1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | WYETH CORP (US) | 2005-12-28 | — | — | EP | claimed |
| EP-1173433-B1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | WYETH CORP (US) | 2005-12-28 | — | — | EP | disclosed |