SCHEMBL6407847

SCHEMBL6407847

NC(=Nc1cc[c]cc1)c1cccs1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 5/20 0.72
NOS3 P29474 5/20 0.54
NOS2 P35228 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280369 0.84 NOS1 (1.00) NOS1NOS3NOS2
Iodide SCHEMBL9053048 0.82 NOS1 (0.96) NOS1NOS3NOS2
SCHEMBL4409794 0.81 NOS1 (0.74) NOS1NOS3NOS2
Iodide SCHEMBL4401426 0.79 NOS1 (0.72) NOS1NOS3NOS2
Oxalic Acid SCHEMBL9054584 0.78 NOS1 (0.87) NOS1NOS3NOS2
SCHEMBL6282320 0.77 NOS1 (0.76) NOS1NOS3NOS2
SCHEMBL6282318 0.77 NOS1 (0.76) NOS1NOS3NOS2
Propyne SCHEMBL9046697 0.77 NOS1 (0.84) NOS1NOS3NOS2
SCHEMBL14370704 0.77 NOS1 (0.76) NOS1NOS3NOS2
SCHEMBL27355025 0.77 NOS1 (0.68) NOS1NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602368-A2 Cdc25 phosphatase inhibitors Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) 2005-12-07 EP disclosed