Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197148 | 0.90 | NPC1 (0.81) | NPC1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL4204371 | 0.88 | KMT2A (0.78) | NPC1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4202140 | 0.86 | KMT2A (0.76) | NPC1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4206195 | 0.86 | NPC1 (0.76) | NPC1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11509618 | 0.86 | NPC1 (0.76) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6409127 | 0.84 | SMN1; SMN2 (0.80) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4206785 | 0.84 | RAB9A (0.75) | NPC1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4210981 | 0.84 | KMT2A (0.72) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6410240 | 0.82 | MEN1 (0.70) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6403344 | 0.82 | L3MBTL1 (0.81) | NPC1MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | NPC1 2070/4885MEN1 3562/4885KMT2A 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.