Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405901 | 0.79 | LMNA (0.61) | LMNAPOLBSMN1; SMN2CYP1A2NOTUM | |
| SCHEMBL23451628 | 0.78 | POLB (0.75) | LMNAPOLBSMN1; SMN2CYP1A2NOTUM | |
| SCHEMBL6401623 | 0.77 | NOTUM (0.61) | LMNAPOLBROCK2SMN1; SMN2CYP1A2 | |
| SCHEMBL6406637 | 0.76 | LMNA (0.58) | LMNAPOLBROCK2SMN1; SMN2CYP1A2 | |
| SCHEMBL31686338 | 0.75 | NOTUM (0.58) | LMNAEPHX2POLBROCK2SMN1; SMN2 | |
| SCHEMBL6408074 | 0.74 | POLB (0.50) | TACR3LMNAEPHX2POLBSMN1; SMN2 | |
| SCHEMBL6408055 | 0.73 | HTT (0.54) | POLBROCK2ROCK1SMN1; SMN2CYP1A2 | |
| SCHEMBL8923076 | 0.73 | EPHX2 (0.67) | TACR3TACR2LMNAEPHX2ROCK2 | |
| SCHEMBL11487647 | 0.72 | POLB (0.53) | LMNAPOLBSMN1; SMN2CYP1A2NOTUM | |
| SCHEMBL6404121 | 0.72 | POLB (0.53) | LMNAPOLBSMN1; SMN2CYP1A2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | TACR3 1994/4885TACR2 2976/4885LMNA 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.