Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802099 | 0.88 | KDM4E (0.50) | MAPK10MAPKAPK2TGFBR1MAP4K4CYP3A4 | |
| SCHEMBL14184255 | 0.87 | MAPK10 (0.45) | MAPK10MAPKAPK2TGFBR1RAB9AMEN1 | |
| SCHEMBL27562868 | 0.86 | TGFBR1 (0.54) | MAPK10MAPKAPK2TGFBR1MAP4K4MAPT | |
| SCHEMBL13045222 | 0.86 | MAPK10 (0.44) | MAPK10MAPKAPK2TGFBR1RAB9AMEN1 | |
| SCHEMBL23278789 | 0.85 | TGFBR1 (0.52) | MAPK10MAPKAPK2TGFBR1MAPTTOP1 | |
| Propane SCHEMBL4417404 | 0.85 | MAPKAPK2 (0.50) | MAPK10MAPKAPK2TGFBR1RAB9AMEN1 | |
| SCHEMBL28605297 | 0.82 | MEN1 (0.47) | MAPK10MAPKAPK2TGFBR1RAB9AMEN1 | |
| SCHEMBL19238779 | 0.81 | MAPT (0.55) | MAP4K4MAPTCCR1CCR5CCR8 | |
| SCHEMBL16526776 | 0.79 | CYP1A2 (0.51) | MAPK10TGFBR1RAB9AMEN1NPC1 | |
| SCHEMBL21001790 | 0.78 | DYRK1A (0.59) | MAPK10RAB9AMEN1KMT2AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001849-B1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-26 | — | — | EP | claimed |
| US-20050233233-A1 | Luminescent lanthanide complexes with imine ligands and devices made with such complexes | RADU NORA S | 2005-10-20 | — | — | US | claimed |
| EP-1406909-A1 | LUMINESCENT LANTHANIDE COMPLEXES WITH IMINE LIGANDS AND DEVICES MADE WITH SUCH COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-04-14 | — | — | EP | claimed |
| US-20030129450-A1 | Luminescent lanthanide complexes with imine ligands and devices made with such complexes | LG CHEM, LTD. (KR) | 2003-07-10 | — | — | US | claimed |
| WO-2003008424-A1 | LUMINESCENT LANTHANIDE COMPLEXES WITH IMINE LIGANDS AND DEVICES MADE WITH SUCH COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-01-30 | — | — | WO | claimed |
| EP-2001849-B1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233233-A1 | Luminescent lanthanide complexes with imine ligands and devices made with such complexes | SSB, LARP7, LIG3 | MAPK10 3812/4885MAPKAPK2 4459/4885TGFBR1 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.