Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.68 |
| ▸ | PGR | P06401 | 5/20 | 0.68 |
| ▸ | AR | P10275 | 4/20 | 0.68 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281837 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL6408531 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL4979442 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL3275715 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL3275721 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL4982376 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL3475639 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL3281843 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL4982380 | 1.00 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 | |
| SCHEMBL6406521 | 0.93 | NR3C1 (0.68) | NR3C1PGRARNR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256094-A1 | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein | G. D. SEARLE & COMPANY (US) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256094-A1 | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein | CYP4A11, CYP11B1, CYP17A1 | NR3C1 71/4885PGR 222/4885AR 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.