SCHEMBL6408612

SCHEMBL6408612

O=C(Nc1ccccc1C(=O)O)c1ccc(Oc2ccc3cc(O)ccc3c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.61
SERPINE1 P05121 1/20 0.59
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
DHODH Q02127 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MAPT P10636 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55
PKM P14618 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6408811 0.92 MEN1 (0.64) SERPINE1MEN1KMT2ADHODHNPC1
SCHEMBL8027764 0.90 MEN1 (0.67) SERPINE1MEN1KMT2ADHODHNPC1
SCHEMBL30466712 0.88 MEN1 (0.72) SERPINE1MEN1KMT2ADHODHNPC1
SCHEMBL2025586 0.88 MEN1 (0.72) SERPINE1MEN1KMT2ADHODHNPC1
SCHEMBL6339040 0.88 ELANE (0.62) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL2292518 0.87 SERPINE1 (0.71) SERPINE1MEN1KMT2ADHODHNPC1
SCHEMBL2276745 0.85 SERPINE1 (0.65) SERPINE1MEN1KMT2ANPC1RAB9A
SCHEMBL2330281 0.85 MEN1 (0.69) SERPINE1MEN1KMT2ANPC1RAB9A
SCHEMBL2274898 0.83 SERPINE1 (0.60) SERPINE1MEN1KMT2ANPC1RAB9A
SCHEMBL6337620 0.83 PLK1 (0.60) HCAR2SERPINE1MEN1KMT2ADHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient TEIJIN LIMITED 2005-02-03 US disclosed
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients TEIJIN LIMITED (JP) 2003-11-27 US disclosed
EP-1256341-A1 CANCER REMEDY COMPRISING ANTHRANILIC ACID DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 2002-11-13 EP disclosed
CN-1048239-C Naphthalene deriv. TEIJIN LTD (JP) 2000-01-12 CN disclosed
CN-1153511-A Naphthalene deriv. TEIJIN LTD (JP) 1997-07-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients HCCS, BCOR, CBR1 HCAR2 274/4885SERPINE1 4734/4885MEN1 3155/4885
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient CA9, HCCS, CA7 HCAR2 387/4885SERPINE1 4640/4885MEN1 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.