Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.65 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | GALK1 | P51570 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 1/20 | 0.54 |
| ▸ | PYGM | P11217 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2274898 | 0.96 | SERPINE1 (0.60) | SERPINE1HPSEMAPTTDP1MEN1 | |
| SCHEMBL2271588 | 0.92 | SERPINE1 (0.64) | SERPINE1HPSEMAPTNR1H4GALK1 | |
| SCHEMBL2270621 | 0.90 | GALK1 (0.68) | SERPINE1HPSENR1H4GALK1CASP6 | |
| SCHEMBL8027764 | 0.89 | MEN1 (0.67) | SERPINE1MAPTMEN1NPC1RAB9A | |
| SCHEMBL2273634 | 0.88 | SERPINE1 (0.60) | SERPINE1HPSENR1H4GALK1CASP6 | |
| SCHEMBL2271007 | 0.88 | MEN1 (0.69) | SERPINE1HPSEMAPTNR1H4MEN1 | |
| SCHEMBL2271920 | 0.88 | SERPINE1 (0.57) | SERPINE1HPSEMAPTNR1H4GALK1 | |
| SCHEMBL2272043 | 0.88 | SERPINE1 (0.75) | SERPINE1HPSEMAPTNR1H4GALK1 | |
| SCHEMBL2275467 | 0.88 | CYP2C9 (0.63) | SERPINE1HPSEMAPTNR1H4GALK1 | |
| SCHEMBL2276169 | 0.88 | SERPINE1 (0.60) | SERPINE1HPSEMAPTNR1H4GALK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | SERPINE1 101/4885HPSE 1324/4885MAPT 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.