Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | CDC25A | P30304 | 2/20 | 0.66 |
| ▸ | CDC25B | P30305 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209335 | 0.93 | LMNA (0.77) | MAPTLMNAALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL6192068 | 0.91 | MAPT (0.91) | MAPTLMNAALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL6274937 | 0.88 | MAPT (0.77) | MAPTLMNAALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL6192401 | 0.87 | ALPG (0.74) | MAPTLMNAALDH1A1POLBCDC25A | |
| SCHEMBL6210228 | 0.86 | MAPT (0.71) | MAPTLMNAALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL6212432 | 0.86 | LMNA (0.80) | MAPTLMNAALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL6193193 | 0.85 | CDC25A (0.74) | MAPTLMNAALDH1A1L3MBTL1RXFP1 | |
| SCHEMBL6839263 | 0.83 | MAPT (0.85) | MAPTLMNARXFP1POLBCDC25A | |
| SCHEMBL6192012 | 0.83 | ALPG (0.69) | MAPTLMNAALDH1A1RXFP1POLB | |
| SCHEMBL6210137 | 0.83 | POLB (0.89) | MAPTLMNAALDH1A1L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | MAPT 2111/4885LMNA 4116/4885ALDH1A1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.