Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | ALPL | P05186 | 1/20 | 0.74 |
| ▸ | ALPG | P10696 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | CDC25A | P30304 | 2/20 | 0.73 |
| ▸ | CDC25B | P30305 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | RGS12 | O14924 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.66 |
| ▸ | TACR1 | P25103 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209335 | 0.92 | LMNA (0.77) | LMNAALPLALPGHTTCDC25A | |
| SCHEMBL6274937 | 0.91 | MAPT (0.77) | LMNAALPLALPGCDC25ACDC25B | |
| SCHEMBL6210228 | 0.89 | MAPT (0.71) | LMNAALPLALPGCDC25ACDC25B | |
| SCHEMBL6192004 | 0.87 | ALPG (0.75) | LMNAALPLALPGHTTCDC25A | |
| SCHEMBL6844152 | 0.87 | ALPG (0.75) | LMNAALPLALPGHTTCDC25A | |
| SCHEMBL6193193 | 0.86 | CDC25A (0.74) | LMNAALPGHTTCDC25ACDC25B | |
| SCHEMBL6408692 | 0.86 | MAPT (0.79) | LMNAALPGHTTCDC25ACDC25B | |
| SCHEMBL18292561 | 0.85 | MAPT (0.66) | LMNAALPLALPGCDC25ACDC25B | |
| SCHEMBL6212052 | 0.85 | MAPT (0.67) | LMNAALPLALPGHTTCDC25A | |
| SCHEMBL6210137 | 0.85 | POLB (0.89) | LMNACDC25ACDC25BMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597249-A1 | ANTHELMINTIC AGENTS AND INSECTICIDAL COMPOSITIONS | Pharmacia & Upjohn Company LLC (US) | 2005-11-23 | — | — | EP | claimed |
| WO-2004074272-A1 | ANTHELMINTIC AGENTS AND INSECTICIDAL COMPOSITIONS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-09-02 | — | — | WO | claimed |
| US-20040171650-A1 | Novel anthelmintic and insecticidal compositions | LEE BYUNG HYUN (US) | 2004-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171650-A1 | Novel anthelmintic and insecticidal compositions | ACHE, AADAC, BCHE | LMNA 4236/4885ALPL 1729/4885ALPG 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.