SCHEMBL6408911

SCHEMBL6408911

CCN(CC)c1ccc2c(c1)Oc1ccc(Nc3ccccc3F)cc1C21OC(=O)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
FTO Q9C0B1 6/20 0.44
MAPT P10636 6/20 0.44
MEN1 O00255 3/20 0.44
HTT P42858 3/20 0.44
KMT2A Q03164 3/20 0.44
HPGD P15428 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
PRMT1 Q99873 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
LMNA P02545 3/20 0.44
ALDH1A1 P00352 2/20 0.44
USP2 O75604 1/20 0.44
CA12 O43570 4/20 0.40
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30657886 1.00 CYP3A4 (0.47) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6409588 0.91 CYP3A4 (0.44) CYP3A4FTOMAPTMEN1HTT
SCHEMBL30473085 0.91 CYP3A4 (0.47) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6405302 0.91 CYP3A4 (0.47) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6406462 0.89 CYP3A4 (0.50) CYP3A4FTOMAPTMEN1HTT
SCHEMBL11504516 0.88 MEN1 (0.46) CYP3A4FTOMAPTMEN1HTT
SCHEMBL12311116 0.87 CYP3A4 (0.48) CYP3A4FTOMAPTMEN1HTT
SCHEMBL6406609 0.87 MAPT (0.47) CYP3A4FTOMAPTMEN1HTT
SCHEMBL11682974 0.87 CYP3A4 (0.52) CYP3A4FTOMAPTMEN1HTT
SCHEMBL11504597 0.86 CYP3A4 (0.48) CYP3A4FTOMAPTMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP claimed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
US-20240181797-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2024-06-06 US disclosed
EP-4313612-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD Ricoh Company, Ltd. (JP) 2024-02-07 EP disclosed
CN-117083182-A Thermosensitive recording layer forming liquid, thermosensitive recording medium, production method thereof, and image recording method 株式会社理光 2023-11-17 CN disclosed
WO-2022202154-A1 THERMOSENSITIVE RECORDING LAYER FORMING LIQUID, THERMOSENSITIVE RECORDING MEDIUM AND PRODUCTION METHOD THEREOF, AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2022-09-29 WO disclosed
EP-1537853-A1 Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers L'OREAL (FR) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA CYP3A4 2156/4885FTO 488/4885MAPT 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.