Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.75 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.75 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.75 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 0.75 |
| ▸ | NNMT | P40261 | 4/20 | 0.76 |
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | DPP4 | P27487 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.75 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.75 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.75 |
| ▸ | GAPDH | P04406 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | STAT6 | P42226 | 1/20 | 0.75 |
| ▸ | PI4KA | P42356 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.75 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.75 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL6408986 | 1.00 | NNMT (0.76) | NNMTDOT1LKMT2ADPP4MEN1 | |
| Adenosine SCHEMBL8013455 | 0.95 | NNMT (0.70) | NNMTDOT1LKMT2ADPP4MEN1 | |
| Adenosine SCHEMBL8013453 | 0.95 | NNMT (0.70) | NNMTDOT1LKMT2ADPP4MEN1 | |
| Adenosine SCHEMBL27579066 | 0.93 | NNMT (0.77) | NNMTDOT1LKMT2ADPP4MEN1 | |
| S-Adenosylhomocysteine SCHEMBL29130128 | 0.92 | DOT1L (0.87) | NNMTDOT1LKMT2AEHMT2CARM1 | |
| Adenosine SCHEMBL28045831 | 0.92 | DOT1L (0.78) | NNMTDOT1LKMT2ADPP4MEN1 | |
| Homocysteine SCHEMBL28487110 | 0.91 | NNMT (0.75) | NNMTDOT1LKMT2AEHMT2CARM1 | |
| Adenosine SCHEMBL27730810 | 0.91 | DOT1L (0.72) | NNMTDOT1LKMT2ADPP4MEN1 | |
| Adenosine SCHEMBL28294033 | 0.91 | NNMT (0.73) | NNMTDOT1LKMT2ADPP4MEN1 | |
| Adenosine SCHEMBL27683840 | 0.90 | NNMT (0.72) | NNMTDOT1LKMT2ADPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478844-A | Recombinant strain for synthesizing sakura extract, construction method thereof, and method for synthesizing sakura extract by fermentation and application | 南京师范大学 | 2023-07-25 | — | — | CN | claimed |
| WO-2020225946-A1 | METHOD FOR EVALUATING SAMPLE, ANALYSIS METHOD, METHOD FOR DETECTING DEGRADED SAMPLE, MARKER FOR DETECTING DEGRADED BLOOD PLASMA SAMPLE, AND MARKER FOR DETECTING DEGRADED SERUM SAMPLE | 株式会社島津製作所 | 2020-11-12 | — | — | WO | claimed |
| CN-108883138-A | Enhance the production and isolated method of cell-derived vesica | 加利福利亚大学董事会 | 2018-11-23 | — | — | CN | claimed |
| CN-118086420-A | Synthesis method of ergothioneine | 珠海宝锐生物科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117957234-A | Thienopyrrole compounds | 吉利德科学公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117741120-A | Reagent card for quantitatively detecting homocysteine | 江苏扬新生物医药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117241826-A | Compositions and methods for therapeutic delivery | 赛托纳斯治疗公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117004544-B | Genetically engineered bacterium for synthesizing vanillin from head by taking glucose as substrate and application thereof | 北京化工大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-117120450-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117106062-A | S-adenosyl homocysteine conjugate and monoclonal antibody preparation and application | 南京拂晓生物科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117004544-A | Genetically engineered bacterium for synthesizing vanillin from head by taking glucose as substrate and application thereof | 北京化工大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-101246177-A | Homo-type cysteine immunity colloidal gold detecting test paper and method for producing the same | BEIJING HAFO BIOMEDICAL RES CT (CN) | 2008-08-20 | — | — | CN | disclosed |
| CN-101157929-A | Safraninemycin biological synthesis gene cluster | SHANGHAI INST ORGANIC CHEM (CN) | 2008-04-09 | — | — | CN | disclosed |
| CN-1303219-C | Method of screening out model for preparing hydrolase inhibitor of adenosine homocysteine | CHANGCHUN APPLIED CHEMISTRY (CN) | 2007-03-07 | — | — | CN | disclosed |
| CN-1687449-A | Method of screening out model for preparing hydrolase inhibitor of adenosine homocysteine | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-10-26 | — | — | CN | disclosed |
| CN-1687449-A | Method of screening out model for preparing hydrolase inhibitor of adenosine homocysteine | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-10-26 | — | — | CN | disclosed |
| US-20050044582-A1 | Novel polynucleotides and uses therefor | THE CORPORATION OF THE TRUSTEES OF THE ORDER OF THE SISTERS OF MERCY IN QUEENSLAND | 2005-02-24 | — | — | US | disclosed |
| WO-2003055997-A1 | GENOMIC SEQUENCES ENCODING DENDRITIC CELL EXPRESSED S-ADENOSYL HOMOCYSTEINE HYDROLASE LIKE MOLECULES | THE CORPORATION OF THE TRUSTEES OF THE ORDER OF THE SISTERS OF MERCY IN QUEENSLAND (AU) | 2003-07-10 | — | — | WO | disclosed |
| US-5872104-A | BACTERICIDES AND RESISTANT BACTERIA WITH METHYLATION INHIBITORS | ORIDIGM CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |
| WO-1996020010-A1 | COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC | ORIDIGM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |