⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6207345 | 0.97 | — | — | |
| SCHEMBL36990 | 0.81 | CYP2C19 (0.59) | — | |
| SCHEMBL10834211 | 0.81 | CYP2C19 (0.59) | — | |
| SCHEMBL10656542 | 0.78 | — | — | |
| SCHEMBL6398747 | 0.78 | — | — | |
| SCHEMBL11458348 | 0.78 | TRPA1 (0.36) | — | |
| Fluoride SCHEMBL5203462 | 0.78 | CYP2C19 (0.56) | — | |
| Methane SCHEMBL9155165 | 0.78 | CYP2C19 (0.56) | — | |
| Hydrogen Peroxide SCHEMBL16799548 | 0.78 | CYP2C19 (0.56) | — | |
| Water SCHEMBL3865217 | 0.78 | CYP2C19 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999732-B2 | P2X3 receptor antagonists | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2024-06-04 | — | — | US | disclosed |
| CN-112584898-B | P2X 3 Receptor antagonists | 瑞蔻达蒂化学和制药工业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-20210246139-A1 | P2X3 RECEPTOR ANTAGONISTS | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2021-08-12 | — | — | US | disclosed |
| EP-3820566-A1 | P2X3 RECEPTOR ANTAGONISTS | Recordati Industria Chimica E Farmaceutica SPA (IT) | 2021-05-19 | — | — | EP | disclosed |
| CN-112584898-A | P2X3Receptor antagonists | 瑞蔻达蒂化学和制药工业股份有限公司 | 2021-03-30 | — | — | CN | disclosed |
| US-10844459-B2 | Process for extracting and recovering tantalum present in an acid aqueous phase by means of an ionic liquid, and use of such an ionic liquid for extracting the tantalum from an acid aqueous phase | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-11-24 | — | — | US | disclosed |
| EP-3334846-B1 | PROCESSES FOR EXTRACTING AND RECOVERING TANTALUM PRESENT IN AN ACID AQUEOUS PHASE BY MEANS OF AN IONIC LIQUID, AND USE OF SUCH AN IONIC LIQUID FOR EXTRACTING THE TANTALUM FROM AN ACID AQUEOUS PHASE | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2020011921-A1 | P2X3 RECEPTOR ANTAGONISTS | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2020-01-16 | — | — | WO | disclosed |
| EP-3334846-A1 | PROCESSES FOR EXTRACTING AND RECOVERING TANTALUM PRESENT IN AN ACID AQUEOUS PHASE BY MEANS OF AN IONIC LIQUID, AND USE OF SUCH AN IONIC LIQUID FOR EXTRACTING THE TANTALUM FROM AN ACID AQUEOUS PHASE | Centre National De La Recherche Scientifique (FR) | 2018-06-20 | — | — | EP | disclosed |
| US-9975871-B2 | Continuous arycyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |
| US-5665716-A | 24-homo vitamin D derivatives, process for their production and pharmaceutical preparations obtained therefrom | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |
| CN-1106666-A | Pharmaceutical use of 24-homo-vitamin-D-derivative | SCHERING AG (DE) | 1995-08-16 | — | — | CN | disclosed |
| EP-0441467-B1 | Side chain homologes of vitamin D derivatives, process for their preparation, pharmaceutical compositions containing them and their use as medicines | SCHERING AG (DE) | 1994-06-01 | — | — | EP | disclosed |
| EP-0421561-B1 | 24-D-homo-vitamin D-derivatives, a process for their production, pharmaceutical compositions containing them and their use as medicines | SCHERING AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0291798-B1 | HYDROXYALKYLTRIAZOL DERIVATIVES | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| WO-1991012238-A1 | SIDE-CHAIN-HOMOLOGOUS VITAMIN D DERIVATIVES, PROCESS FOR PRODUCING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THESE DERIVATIVES AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-08-22 | — | — | WO | disclosed |
| EP-0441467-A1 | Side chain homologes of vitamin D derivatives, process for their preparation, pharmaceutical compositions containing them and their use as medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0421561-A2 | 24-D-homo-vitamin D-derivatives, a process for their production, pharmaceutical compositions containing them and their use as medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0291798-A2 | Hydroxyalkyltriazol derivatives | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4240983-A | HALOGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | disclosed |