Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408206 | 0.79 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1GAA | |
| SCHEMBL17214887 | 0.74 | ALDH1A1 (0.41) | POLBCSNK2A2CSNK2A1ALDH1A1TDP1 | |
| SCHEMBL11887741 | 0.74 | TYMP (0.57) | ALDH1A1TDP1KMT2AGAAKDM4E | |
| SCHEMBL6405997 | 0.74 | KMT2A (0.39) | POLBCSNK2A2CSNK2A1ALDH1A1TDP1 | |
| SCHEMBL17214763 | 0.73 | KMT2A (0.42) | POLBALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL17214848 | 0.72 | GAA (0.44) | POLBCSNK2A2CSNK2A1ALDH1A1TDP1 | |
| SCHEMBL14478829 | 0.72 | LMNA (0.63) | POLBALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL17214845 | 0.72 | ALDH1A1 (0.44) | POLBCSNK2A2CSNK2A1ALDH1A1TDP1 | |
| SCHEMBL17214886 | 0.72 | KMT2A (0.41) | POLBALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL17213026 | 0.71 | GRK6 (0.46) | POLBALDH1A1TDP1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | POLB 854/4885CSNK2A2 3286/4885CSNK2A1 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.