⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909433 | 0.77 | CYP2C19 (0.34) | — | |
| SCHEMBL14669634 | 0.74 | CYP3A4 (0.32) | — | |
| SCHEMBL2361873 | 0.73 | — | — | |
| SCHEMBL45787 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL10426281 | 0.70 | TDP1 (0.36) | — | |
| SCHEMBL7951229 | 0.70 | CPT2 (0.32) | — | |
| SCHEMBL29008273 | 0.69 | — | — | |
| SCHEMBL28430073 | 0.69 | HTT (0.36) | — | |
| SCHEMBL7106652 | 0.68 | — | — | |
| SCHEMBL2874532 | 0.68 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150240226-A1 | NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM | BP CORP NORTH AMERICA INC (US) | 2015-08-27 | — | — | US | disclosed |
| US-8962800-B2 | Nucleic acids and proteins and methods for making and using them | BP CORPORATION NORTH AMERICA INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120266329-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | BP CORPORATION NORTH AMERICA INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-8119385-B2 | Nucleic acids and proteins and methods for making and using them | BP CORPORATION NORTH AMERICA INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110296543-A1 | NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM | THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-01 | — | — | US | disclosed |
| US-20100011456-A1 | Nucleic Acids and Proteins and Methods for Making and Using Them | VERENIUM CORPORATION (US) | 2010-01-14 | — | — | US | disclosed |