SCHEMBL7951229

SCHEMBL7951229

CC(=O)C(O)C(O)(CO)C(C)=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CPT2 P23786 1/20 0.32
ACLY P53396 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTGS1 P23219 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9055900 0.80
SCHEMBL10426281 0.80 TDP1 (0.36) ALDH1A1TDP1
SCHEMBL8909433 0.78 CYP2C19 (0.34)
SCHEMBL7542700 0.77 ALDH1A1 (0.38) ALDH1A1TDP1
SCHEMBL29008273 0.75
SCHEMBL27431574 0.74 ALDH1A1 (0.33) ALDH1A1TDP1PTGS1KCNH2
SCHEMBL5667944 0.73
SCHEMBL10074938 0.72 PTGS1 (0.48) ALDH1A1TDP1PTGS1KCNH2
SCHEMBL640918 0.70
SCHEMBL5859283 0.70 TSHR (0.41) CPT2ACLYALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 EP claimed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 EP claimed
WO-1996009810-A1 METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-04 WO claimed
US-6267948-B1 ADMINISTERING TO MAMMALIAN SKIN, HAIR, WOOL OR FUR DERMATOLOGICAL FORMULATION CONTAINING MELANOGENESIS STIMULATING AGENT WHICH STIMULATES MELANOGENESIS IN MELANOCYTES AND HYDROXY ACID TO ENHANCE MELANOGENESIS APPLIED GENETICS INCORPORATED DERMATICS 2001-07-31 US disclosed
CN-1253588-A Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants ABBOTT LAB (US) 2000-05-17 CN disclosed
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 EP disclosed
WO-1999051198-A1 DERMATOLOGICAL FORMULATIONS AND METHODS CODON PHARMACEUTICALS, INC. (US) 1999-10-14 WO disclosed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 EP disclosed
US-5750091-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1998-05-12 US disclosed
US-5700450-A Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1997-12-23 US disclosed
US-5352440-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 1994-10-04 US disclosed
US-5215973-A Treating anhydrous form with water; crystallization from organic solvent of medium polarity; antilipemic agents MAGIS FARMACEUTICI S.P.A. (IT) 1993-06-01 US disclosed
EP-0502357-A1 Optically active and racemic hydrated diacetylesters of alpha-glycero-phosphoryl-choline MAGIS FARMACEUTICI S.p.A. (IT) 1992-09-09 EP disclosed
EP-0373195-A1 COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. TUFTS COLLEGE (US) 1990-06-20 EP disclosed
EP-0373195-A4 COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. TUFTS COLLEGE (US) 1990-05-14 EP disclosed
WO-1989009258-A1 METHODS FOR INCREASING MELANIN CONTENT AND FOR INDUCING MELANOCYTE PROLIFERATION IN-VIVO AND IN-VITRO TRUSTEES OF TUFTS COLLEGE (US) 1989-10-05 WO disclosed
EP-0002062-B1 CYCLIC ORGANOPHOSPHORUS COMPOUNDS, METHOD FOR THEIR PREPARATION AND THEIR USE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1982-05-05 EP disclosed
EP-0036155-A2 Polymerisable phospholipids, process for their preparation, polymeric phospholipids, process for their preparation as well as the use of the polymeric phospholipids Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1981-09-23 EP disclosed
EP-0002062-A1 Cyclic organophosphorus compounds, method for their preparation and their use Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1979-05-30 EP disclosed