Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492502 | 1.00 | GAA (0.79) | GAANPC1CYP3A4TSHRPTK2 | |
| SCHEMBL204719 | 0.89 | GAA (0.86) | GAANPC1CYP3A4TSHRPTK2 | |
| SCHEMBL64092 | 0.88 | GAA (1.00) | GAANPC1CYP3A4TSHRPTK2 | |
| Hydrochloric Acid SCHEMBL28016984 | 0.85 | GAA (0.92) | GAANPC1CYP3A4TSHRPTK2 | |
| SCHEMBL26746409 | 0.79 | GAA (0.69) | GAANPC1CYP3A4TSHRPTK2 | |
| SCHEMBL23716737 | 0.78 | GAA (0.58) | GAANPC1CYP3A4TSHRTP53 | |
| SCHEMBL6666210 | 0.78 | GAA (0.58) | GAANPC1CYP3A4TSHRPTK2 | |
| SCHEMBL454590 | 0.78 | TSHR (0.60) | GAANPC1CYP3A4TSHRTP53 | |
| SCHEMBL23974410 | 0.78 | GAA (0.58) | GAANPC1CYP3A4TSHRTP53 | |
| SCHEMBL15797869 | 0.78 | GAA (0.58) | GAANPC1CYP3A4TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230126543-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| US-20230126543-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| US-11161807-B2 | Thermo-thickening compounds for non-polar liquid | SORBONNE UNIVERSITE (FR) | 2021-11-02 | — | — | US | disclosed |
| CN-107501099-B | Modulators of ATP-binding cassette transporters | 沃泰克斯药物股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| US-4070353-A | FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4065449-A | Tetrachloro substituted disazo pigments | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
| US-4053464-A | DISAZO PIGMENTS CONTAINING ETHER SUBSTITUTED ALKOXY CARBONYL GROUPS | CIBA-GEIGY CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4046755-A | CELLULOSE ETHERS, POLYAMIDES, POLYURETHANES, ACRYLICS | CIBA-GEIGY CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-4003886-A | Tetracarboxylic acid ester substituted disazo pigments | CIBA-GEIGY AG (CH) | 1977-01-18 | — | — | US | disclosed |
| US-3993679-A | ANTIALLERGY | THE UPJOHN COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3988312-A | TETRAKISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3978038-A | POLYAMIDES, POLYESTERS, POLYURETHANES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3956266-A | DISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | GAA 454/4885NPC1 28/4885CYP3A4 1862/4885 |
| US-20230126543-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | CYP1A1, AOX1, CRY1 | GAA 1515/4885NPC1 2471/4885CYP3A4 26/4885 |
| US-11161807-B2 | Thermo-thickening compounds for non-polar liquid | PUF60, NONO, MAPT | GAA 2507/4885NPC1 2074/4885CYP3A4 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.