Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 12/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958379 | 0.79 | KCNH2 (0.46) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2964453 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1MAPTKMT2A | |
| SCHEMBL6417212 | 0.70 | DPP4 (0.33) | DPP4CHRM1 | |
| SCHEMBL6422754 | 0.70 | DPP4 (0.44) | DPP4CHRM1 | |
| SCHEMBL2965832 | 0.70 | DPP4 (0.46) | DPP4CHRM1 | |
| SCHEMBL6410010 | 0.70 | DPP4 (0.45) | DPP4CHRM1 | |
| SCHEMBL6425924 | 0.69 | DPP4 (0.42) | ALDH1A1DPP4CHRM1 | |
| SCHEMBL6425388 | 0.69 | DPP4 (0.43) | ALDH1A1DPP4CHRM1 | |
| SCHEMBL13217491 | 0.68 | KCNH2 (0.54) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6450605 | 0.67 | DPP4 (0.45) | DPP4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |