Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425924 | 0.93 | DPP4 (0.42) | DPP4CHRM1FAP | |
| SCHEMBL6425388 | 0.92 | DPP4 (0.43) | DPP4CHRM1FAP | |
| SCHEMBL6425261 | 0.82 | ALDH1A1 (0.52) | DPP4CHRM1CHRM3 | |
| SCHEMBL5719040 | 0.80 | DPP4 (0.42) | DPP4FAPDPP9 | |
| SCHEMBL5776712 | 0.76 | GAA (0.39) | DPP4DPP9 | |
| SCHEMBL5772185 | 0.76 | HIF1A (0.36) | DPP4CHRM1CHRM3 | |
| SCHEMBL5771832 | 0.75 | TRPA1 (0.34) | DPP4DPP9 | |
| SCHEMBL6424057 | 0.74 | DPP4 (0.39) | DPP4CHRM1CHRM3 | |
| SCHEMBL5719478 | 0.73 | DPP4 (0.40) | DPP4DPP9 | |
| SCHEMBL5718962 | 0.73 | DPP4 (0.41) | DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |