Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425388 | 0.98 | DPP4 (0.43) | DPP4CHRM1FAPALDH1A1SMN1; SMN2 | |
| SCHEMBL6422754 | 0.93 | DPP4 (0.44) | DPP4CHRM1FAP | |
| SCHEMBL5719478 | 0.82 | DPP4 (0.40) | DPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL5718962 | 0.80 | DPP4 (0.41) | DPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL6425261 | 0.78 | ALDH1A1 (0.52) | DPP4CHRM1ALDH1A1 | |
| SCHEMBL5719040 | 0.74 | DPP4 (0.42) | DPP4FAP | |
| Trifluoroacetic Acid SCHEMBL5718899 | 0.72 | DPP4 (0.57) | DPP4FAPALDH1A1SMN1; SMN2 | |
| SCHEMBL5776712 | 0.71 | GAA (0.39) | DPP4ALDH1A1SMN1; SMN2 | |
| SCHEMBL5719799 | 0.71 | DPP4 (0.59) | DPP4CHRM1FAPALDH1A1SMN1; SMN2 | |
| SCHEMBL5772185 | 0.71 | HIF1A (0.36) | DPP4CHRM1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |