Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407156 | 0.85 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL19921872 | 0.83 | TSHR (0.46) | TSHRFAAHMAPTUSP2LMNA | |
| SCHEMBL28565937 | 0.81 | TSHR (0.42) | TSHRFAAHALDH1A1MAPTUSP2 | |
| Methacrylic Acid SCHEMBL15392574 | 0.80 | TSHR (0.48) | TSHRFAAHTRPV1HIF1AMAPT | |
| SCHEMBL3624636 | 0.79 | ALDH1A1 (0.33) | ALDH1A1USP2 | |
| SCHEMBL15524747 | 0.78 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTUSP2LMNA | |
| SCHEMBL7132092 | 0.78 | ALDH1A1 (0.37) | TSHRALDH1A1TDP1 | |
| Methacrylic Acid SCHEMBL7785580 | 0.78 | TSHR (0.44) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| Methacrylic Acid SCHEMBL3305565 | 0.78 | TSHR (0.44) | TSHRFAAHTRPV1HIF1AALDH1A1 | |
| SCHEMBL487125 | 0.76 | TSHR (0.38) | TSHRALDH1A1MAPTUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050207978-A1 | Dental-caries detecting solution | NIPPON SHIKA YAKUHIN KK. (JP) | 2005-09-22 | — | — | US | disclosed |