Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | TK2 | O00142 | 9/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655055 | 1.00 | RNASE1 (0.46) | RNASE1TK1TK2TYMP | |
| SCHEMBL6409396 | 1.00 | RNASE1 (0.46) | RNASE1TK1TK2TYMP | |
| SCHEMBL7266100 | 0.91 | RNASE1 (0.49) | RNASE1TK1TK2TYMP | |
| SCHEMBL6830771 | 0.89 | RNASE1 (0.51) | RNASE1TK1TYMP | |
| SCHEMBL6832157 | 0.88 | RNASE1 (0.49) | RNASE1TK1TK2 | |
| SCHEMBL6827418 | 0.88 | RNASE1 (0.53) | RNASE1TK1TK2 | |
| SCHEMBL6323173 | 0.88 | RNASE1 (0.51) | RNASE1TK1TK2TYMP | |
| SCHEMBL9393197 | 0.87 | TK1 (0.59) | RNASE1TK1TYMP | |
| SCHEMBL6831287 | 0.86 | RNASE1 (0.47) | RNASE1TK1TYMP | |
| SCHEMBL23045153 | 0.86 | RNASE1 (0.57) | RNASE1TK1TK2TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891033-B2 | Chemical intermediates such as 3-N-Boc-1-(5-O-(4,4'-dimethoxytrityl)-3-O-nosyl-2-deoxy-beta-D -lyxofuranosyl)thymine; use of final compound in positron emission tomography (PET) | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2005-05-10 | — | — | US | disclosed |
| US-20040110720-A1 | Labelling compounds for the simple synthesis of 3'-(18f)fluoro-3'-deoxy thymidine and a method for the production thereof | DEUTCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES O'FFENTLICHEN RECHTS (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110720-A1 | Labelling compounds for the simple synthesis of 3'-(18f)fluoro-3'-deoxy thymidine and a method for the production thereof | TK1, TYMS, TYMP | RNASE1 873/4885TK1 1/4885TK2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.