Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412394 | 0.86 | HRH3 (0.59) | HRH3 | |
| SCHEMBL19088665 | 0.80 | HRH3 (0.64) | HRH3MAPTBCHERORC | |
| SCHEMBL6405789 | 0.78 | TSHR (0.48) | HRH3BCHERORCCYP1A2CYP2D6 | |
| SCHEMBL20287494 | 0.77 | HRH3 (0.72) | HRH3MAPTBCHERORCCYP1A2 | |
| SCHEMBL6410635 | 0.77 | HRH3 (0.56) | HRH3 | |
| SCHEMBL15831721 | 0.76 | HRH3 (0.59) | HRH3MAPTRORC | |
| SCHEMBL1206711 | 0.75 | HRH3 (0.69) | HRH3MAPTBCHECYP1A2CYP2D6 | |
| SCHEMBL14640185 | 0.75 | HRH3 (0.69) | HRH3MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13078725 | 0.75 | HRH3 (0.69) | HRH3MAPTBCHECYP1A2CYP2D6 | |
| SCHEMBL12894414 | 0.75 | HRH3 (0.69) | HRH3MAPTBCHECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222098-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2005-10-06 | — | — | US | disclosed |
| EP-0767798-B1 | STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS | NOVO NORDISK AS (DK) | 2003-09-03 | — | — | EP | disclosed |
| US-20030004148-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222098-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | HRH3 3595/4885MAPT 3666/4885BCHE 3553/4885 |
| US-20030004148-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | HRH3 3595/4885MAPT 3666/4885BCHE 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.