Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5506486 | 0.87 | KCNH2 (0.45) | KCNH2SMN1; SMN2MAPTALDH1A1SETD7 | |
| SCHEMBL3131638 | 0.75 | SETD7 (0.51) | KCNH2SETD7HRH1 | |
| SCHEMBL3131124 | 0.74 | HRH1 (0.57) | KCNH2SETD7LMNAADRA1DADRA1A | |
| SCHEMBL14318737 | 0.74 | KCNH2 (0.67) | KCNH2SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL14307767 | 0.74 | ALDH1A1 (0.51) | KCNH2SMN1; SMN2MAPTALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL3136931 | 0.73 | SETD7 (0.44) | KCNH2MAPTALDH1A1SETD7KDM4E | |
| SCHEMBL3037204 | 0.73 | KDM4E (0.39) | KCNH2GPR84SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3131282 | 0.73 | SETD7 (0.57) | KCNH2MAPTALDH1A1SETD7KMT2A | |
| SCHEMBL3147395 | 0.72 | NPC1 (0.48) | KCNH2SMN1; SMN2MAPTALDH1A1SETD7 | |
| Hydrochloric Acid SCHEMBL3039118 | 0.72 | KDM4E (0.39) | KCNH2GPR84SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288283-A1 | Topical formulations for treating allergic diseases | ALCON, INC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288283-A1 | Topical formulations for treating allergic diseases | TSLP, HRH2, HRH1 | KCNH2 1917/4885GPR84 602/4885SMN1; SMN2 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.