Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401286 | 0.87 | CNR2 (0.44) | ALDH1A1POLBCNR2CNR1TDP1 | |
| SCHEMBL6416605 | 0.86 | POLB (0.43) | ALDH1A1RAB9APOLBTDP1EPHX2 | |
| SCHEMBL6409707 | 0.85 | MAPK8 (0.51) | ALDH1A1 | |
| SCHEMBL15309149 | 0.79 | TDP1 (0.44) | ALDH1A1POLBTDP1 | |
| SCHEMBL2403591 | 0.74 | MAPK8 (0.57) | ALDH1A1 | |
| SCHEMBL2400992 | 0.73 | TDP1 (0.46) | ALDH1A1POLBTDP1 | |
| SCHEMBL6412218 | 0.73 | ALDH1A1 (0.40) | ALDH1A1RAB9APOLB | |
| SCHEMBL6410889 | 0.73 | MAPT (0.39) | ALDH1A1POLBTDP1EPHX2 | |
| SCHEMBL2583086 | 0.71 | CYP2C19 (0.44) | ALDH1A1RAB9APOLBCNR2CNR1 | |
| SCHEMBL6411430 | 0.69 | RAB9A (0.47) | ALDH1A1RAB9APOLBTDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | claimed |
| EP-1521828-A2 | PRODUCTION OF POLYKETIDES | Biotica Technology Limited (GB) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007709-A2 | PRODUCTION OF POLYKETIDES | BIOTICA TECHNOLOGY LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1401841-B1 | SUBSTITUTED 1-OXA-2,8-DIAZA-SPIRO 4,5]DEC-2-ENE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF PAIN | GRUENENTHAL GMBH (DE) | 2005-08-24 | — | — | EP | disclosed |