SCHEMBL6409645

SCHEMBL6409645

O=C(O)C1CC1COCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 15/20 0.62
NAAA Q02083 1/20 0.48
FFAR1 O14842 1/20 0.45
EPHX1 P07099 1/20 0.44
AGTR2 P50052 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29188003 0.91 FFAR4 (0.57) FFAR4AGTR2
SCHEMBL17391191 0.91 FFAR4 (0.57) FFAR4AGTR2
SCHEMBL29018749 0.91 FFAR4 (0.57) FFAR4AGTR2
SCHEMBL5447182 0.91 FFAR4 (0.57) FFAR4AGTR2
SCHEMBL5924916 0.91 FFAR4 (0.57) FFAR4AGTR2
SCHEMBL6406962 0.86 FFAR4 (0.49) FFAR4NAAAEPHX1
SCHEMBL17593072 0.85 FFAR4 (0.53) FFAR4FFAR1AGTR2
SCHEMBL17593073 0.85 FFAR4 (0.53) FFAR4FFAR1AGTR2
SCHEMBL27606275 0.84 FFAR4 (0.48) FFAR4
SCHEMBL6412514 0.84 CA12 (0.48) FFAR4NAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
CN-1681767-A Method for manufacturing 2-(hydroxymethyl) cyclopropane carboxylic acid compound SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 FFAR4 2429/4885NAAA 1503/4885FFAR1 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.