Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392319 | 1.00 | HPGD (0.73) | HPGDL3MBTL1MAPK1GAATSHR | |
| SCHEMBL3654191 | 0.89 | PDE7A (0.63) | HPGDL3MBTL1MAPK1TSHRHSP90AA1 | |
| SCHEMBL4912854 | 0.88 | HPGD (0.73) | HPGDL3MBTL1MAPK1GAATSHR | |
| SCHEMBL16296010 | 0.88 | HPGD (0.73) | HPGDL3MBTL1MAPK1GAATSHR | |
| SCHEMBL4965836 | 0.87 | MAPK1 (0.62) | HPGDL3MBTL1MAPK1TSHRHSP90AA1 | |
| SCHEMBL11229678 | 0.87 | HPGD (0.55) | HPGDL3MBTL1MAPK1GAATSHR | |
| SCHEMBL3039145 | 0.86 | HPGD (0.71) | HPGDL3MBTL1MAPK1GAAHSP90AA1 | |
| SCHEMBL9266291 | 0.85 | HPGD (1.00) | HPGDL3MBTL1MAPK1GAAHSP90AA1 | |
| SCHEMBL3050533 | 0.85 | HPGD (0.69) | HPGDL3MBTL1MAPK1GAAHSP90AA1 | |
| SCHEMBL9965425 | 0.85 | HPGD (0.69) | HPGDL3MBTL1MAPK1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710167-B | Two diphenyl ether compounds, preparation method and application thereof in preparation of antibacterial drugs | 中国科学院南海海洋研究所 | 2024-04-16 | — | — | CN | disclosed |
| CN-115710167-A | Two diphenyl ether compounds, preparation method thereof and application thereof in preparation of antibacterial drugs | 中国科学院南海海洋研究所 | 2023-02-24 | — | — | CN | disclosed |
| EP-3061750-B1 | PYRAZOLE AMIDE COMPOUNDS CONTAINING A DIPHENYL ETHER GROUP, AND APPLICATION THEREOF, AND PESTICIDE COMPOSITION | UNIV CENTRAL CHINA NORMAL (CN) | 2018-03-28 | — | — | EP | disclosed |
| EP-3061750-A1 | PYRAZOLE AMIDE COMPOUND CONTAINING DIPHENYL ETHER, AND APPLICATION THEREOF, AND PESTICIDE COMPOSITION | Central China Normal University (CN) | 2016-08-31 | — | — | EP | disclosed |
| CN-105076150-A | Bactericide composition and preparation and application thereof | UNIV HUAZHONG NORMAL | 2015-11-25 | — | — | CN | disclosed |
| CN-104904721-A | Fungicide composition, preparation of fungicide composition and application of preparation | UNIV HUAZHONG NORMAL | 2015-09-16 | — | — | CN | disclosed |
| CN-104872136-A | Bactericide composition and preparation as well as application thereof | UNIV HUAZHONG NORMAL | 2015-09-02 | — | — | CN | disclosed |
| CN-104557709-A | Pyrazole amide compound containing diphenyl ether, and application and pesticide composition of pyrazole amide compound | UNIV HUAZHONG NORMAL | 2015-04-29 | — | — | CN | disclosed |
| WO-2014199164-A1 | DIARYL SUBSTITUTED HETEROAROMATIC COMPOUNDS | AMPLA PHARMACEUTICALS, INC. (US) | 2014-12-18 | — | — | WO | disclosed |
| EP-2076491-B1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-07-17 | — | — | EP | disclosed |
| EP-1960347-A2 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | Sterix Limited (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008068540-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008050167-A1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008050168-A1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |
| EP-0848703-A1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | Nycomed Austria GmbH (AT) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997003953-A1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 1997-02-06 | — | — | WO | disclosed |