Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637473 | 0.85 | PDE7A (0.72) | HPGDL3MBTL1PDE7AMEN1KMT2A | |
| SCHEMBL30392319 | 0.85 | HPGD (0.73) | HPGDL3MBTL1PDE7AGAAMEN1 | |
| SCHEMBL640965 | 0.85 | HPGD (0.73) | HPGDL3MBTL1PDE7AGAAMEN1 | |
| SCHEMBL3039145 | 0.84 | HPGD (0.71) | HPGDL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9266291 | 0.82 | HPGD (1.00) | HPGDL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL3050533 | 0.82 | HPGD (0.69) | HPGDL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL16296141 | 0.81 | LMNA (0.68) | HPGDL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL11757143 | 0.80 | PDE7A (0.78) | HPGDPDE7AGAAMEN1KMT2A | |
| SCHEMBL8101216 | 0.80 | HPGD (0.66) | HPGDL3MBTL1PDE7AGAAMEN1 | |
| SCHEMBL3137542 | 0.80 | HPGD (0.66) | HPGDL3MBTL1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |