Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442037 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL7675649 | 0.77 | MAOB (0.54) | ALDH1A1HPGD | |
| SCHEMBL6236448 | 0.76 | CA12 (0.48) | ALDH1A1MAPTHSD17B10GAACA12 | |
| SCHEMBL9489701 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL4360840 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL17187941 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1MAPTMAPK1GLA | |
| SCHEMBL6871666 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1MAPTMAPK1PKM | |
| SCHEMBL9579625 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL7121659 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL6441929 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1MAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562951-A2 | PORPHYRIN DERIVATIVES | Photobiotics Ltd. (GB) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046151-A2 | PORPHYRIN DERIVATIVES | PHOTOBIOTICS LIMITED (GB) | 2004-06-03 | — | — | WO | disclosed |