Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193452 | 0.87 | CYP3A4 (0.70) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL30976995 | 0.87 | CYP3A4 (0.70) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL31364552 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL344841 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL4360840 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL11312620 | 0.84 | CYP3A4 (0.53) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL8839069 | 0.83 | RXRA (0.50) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL6271897 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL996990 | 0.83 | HPGD (0.74) | KDM4EALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL1207513 | 0.82 | CA12 (0.66) | KDM4EALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985927-A | Medicaments for the selective treatment of tumor tissues | KREUTZ WERNER (DE) | 1999-11-16 | — | — | US | claimed |
| CN-118724760-A | Preparation method of amido guanidine compound and myocardial protection effect thereof | 天津理工大学 | 2024-10-01 | — | — | CN | disclosed |
| US-20230137472-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-04 | — | — | US | disclosed |
| US-20230137472-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-04 | — | — | US | disclosed |
| US-9012838-B2 | Covalently functionalized nanodiamond-based MALDI matrices and methods of use thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2015-04-21 | — | — | US | disclosed |
| US-20140312218-A1 | COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2014-10-23 | — | — | US | disclosed |
| EP-0817623-B1 | MEDICAMENTS FOR THE SELECTIVE TREATMENT OF TUMOUR TISSUES | KREUTZ WERNER PROF DR (DE) | 2003-11-12 | — | — | EP | disclosed |
| US-5985927-A | Medicaments for the selective treatment of tumor tissues | KREUTZ WERNER (DE) | 1999-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140312218-A1 | COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF | ITGA2B, MMP2, ITGAV | KDM4E 2997/4885ALDH1A1 1988/4885CA12 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.