Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954508 | 0.88 | DPP4 (0.36) | DPP4 | |
| SCHEMBL2964028 | 0.85 | DPP4 (0.45) | DPP4MEN1KMT2A | |
| SCHEMBL2966572 | 0.84 | DPP4 (0.33) | DPP4 | |
| SCHEMBL2965090 | 0.84 | DPP4 (0.31) | DPP4 | |
| SCHEMBL2957134 | 0.81 | — | — | |
| SCHEMBL2961605 | 0.79 | NPBWR1 (0.36) | DPP4ATMMEN1KMT2AGAA | |
| SCHEMBL2952265 | 0.79 | DPP4 (0.33) | DPP4 | |
| SCHEMBL2957734 | 0.79 | NPC1 (0.35) | DPP4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2952472 | 0.79 | DRD2 (0.35) | DPP4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2956620 | 0.78 | MRGPRX1 (0.33) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |