Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.55 |
| ▸ | CCR5 | P51681 | 16/20 | 0.53 |
| ▸ | CCR7 | P32248 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342711 | 0.97 | CCR2 (0.55) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6350730 | 0.96 | CCR2 (0.53) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6344086 | 0.95 | CCR2 (0.57) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6340941 | 0.95 | CCR5 (0.58) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6343375 | 0.95 | CCR2 (0.55) | CCR2CCR5CCR7CCR3CCR4 | |
| Hydrochloric Acid SCHEMBL6339046 | 0.95 | CCR2 (0.53) | CCR2CCR5CCR7CCR3CCR4 | |
| Hydrochloric Acid SCHEMBL6350443 | 0.95 | CCR5 (0.57) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6350472 | 0.94 | CCR2 (0.53) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL6341653 | 0.94 | CCR2 (0.54) | CCR2CCR5CCR7CCR3CCR4 | |
| SCHEMBL3029085 | 0.94 | CCR2 (0.56) | CCR2CCR5CCR7CCR3CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |