Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404676 | 1.00 | L3MBTL1 (0.62) | L3MBTL1SMN1; SMN2LMNAPOLBCYP3A4 | |
| SCHEMBL6403486 | 0.88 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2LMNAPOLBCYP3A4 | |
| SCHEMBL6404748 | 0.85 | GAA (0.60) | L3MBTL1SMN1; SMN2LMNAPOLBKMT2A | |
| SCHEMBL6404661 | 0.85 | KMT2A (0.51) | L3MBTL1SMN1; SMN2LMNAPOLBCYP3A4 | |
| SCHEMBL6404027 | 0.81 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2LMNAPOLBNPSR1 | |
| SCHEMBL11391926 | 0.77 | KMT2A (0.49) | L3MBTL1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30366678 | 0.77 | CYP3A4 (0.63) | L3MBTL1SMN1; SMN2LMNAPOLBCYP3A4 | |
| SCHEMBL11384854 | 0.77 | TLR8 (0.44) | L3MBTL1SMN1; SMN2LMNACYP3A4CYP2C9 | |
| SCHEMBL6405215 | 0.76 | GAA (0.62) | L3MBTL1SMN1; SMN2LMNAPOLBKMT2A | |
| SCHEMBL6406630 | 0.76 | GAA (0.62) | L3MBTL1SMN1; SMN2LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | L3MBTL1 2749/4885SMN1; SMN2 4793/4885LMNA 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.