Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403533 | 0.89 | ALDH1A1 (0.55) | GAAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6406630 | 0.88 | GAA (0.62) | GAAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6404661 | 0.85 | KMT2A (0.51) | GAAKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6403944 | 0.81 | ALDH1A1 (0.60) | GAAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6404748 | 0.78 | GAA (0.60) | GAAKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6408598 | 0.78 | LMNA (0.61) | GAAKDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6404676 | 0.76 | L3MBTL1 (0.62) | GAAKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6411070 | 0.76 | L3MBTL1 (0.62) | GAAKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6403486 | 0.74 | L3MBTL1 (0.49) | GAAKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6409638 | 0.71 | ALDH1A1 (0.63) | GAAKDM4EALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | GAA 85/4885KDM4E 3676/4885ALDH1A1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.