Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030940 | 0.83 | ADRB1 (0.49) | ADRB1ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL28396664 | 0.79 | ADRB1 (0.71) | HTR1AADRB1KDM4EALDH1A1PLA2G1B | |
| SCHEMBL6032145 | 0.78 | MAPT (0.51) | HTR1AADRB1ALDH1A1IGF1RDRD2 | |
| SCHEMBL13898923 | 0.77 | ADRB1 (0.53) | HTR1AADRB1KDM4EALDH1A1PLA2G1B | |
| SCHEMBL9417733 | 0.75 | CYP2D6 (0.61) | HTR1AALDH1A1LMNADRD3SLC6A2 | |
| SCHEMBL19212308 | 0.74 | ADRB1 (0.59) | HTR1AADRB1KDM4EALDH1A1PLA2G1B | |
| SCHEMBL3210638 | 0.74 | CYP1A2 (0.63) | KDM4EALDH1A1LMNA | |
| SCHEMBL6031006 | 0.73 | MAPT (0.48) | HTR1AADRB1KDM4EALDH1A1RAB9A | |
| Bromide SCHEMBL6030911 | 0.73 | MEN1 (0.55) | HTR1AADRB1ALDH1A1LMNAHTT | |
| SCHEMBL3928716 | 0.72 | CYP2D6 (0.42) | HTR1AKDM4ELMNADRD3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239799-A1 | 1-phenyl-4-benzylpiperazines dopamine receptor subtype | NEUROGEN CORPORATION (US) | 2005-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239799-A1 | 1-phenyl-4-benzylpiperazines dopamine receptor subtype | DRD2, DRD4, HTR2C | HTR1A 6/4885ADRB1 113/4885KDM4E 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.