Phosphoric Acid

Phosphoric Acid

SCHEMBL641209

O=P(O)(O)O.c1ccc(-c2ccc3ccccc3c2-c2ccccc2)cc1

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.46
DNMT1 P26358 1/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
GPR84 Q9NQS5 3/20 0.44
KDM4E B2RXH2 3/20 0.44
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
MAPT P10636 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
MPI P34949 1/20 0.41
ACP3 P15309 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX5 P09917 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191449 0.89 DNMT1 (0.48) WDR5DNMT1MEN1KMT2AGPR84
SCHEMBL30034855 0.89 DNMT1 (0.48) WDR5DNMT1MEN1KMT2AGPR84
Phosphine SCHEMBL28227864 0.87 DNMT1 (0.47) WDR5DNMT1MEN1KMT2AGPR84
Methane SCHEMBL28083172 0.87 DNMT1 (0.47) WDR5DNMT1MEN1KMT2AGPR84
Ammonia Solution, Strong SCHEMBL12818906 0.87 DNMT1 (0.47) WDR5DNMT1MEN1KMT2AGPR84
Hydrogen Sulfide SCHEMBL28212457 0.87 DNMT1 (0.47) WDR5DNMT1MEN1KMT2AGPR84
SCHEMBL29321981 0.83 DNMT1 (0.44) WDR5DNMT1MEN1KMT2AGPR84
SCHEMBL11333610 0.83 DNMT1 (0.46) WDR5DNMT1MEN1KMT2AGPR84
Phosphoric Acid SCHEMBL27982532 0.82 HDAC4 (0.45) GPR84CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL17442108 0.82 ALDH1A1 (0.50) WDR5DNMT1MEN1KMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112080125-B Protective case member for mobile battery pack 旭化成株式会社 2023-05-23 CN disclosed
CN-111406086-B Vehicle-mounted lithium ion battery component 旭化成株式会社 2023-04-28 CN disclosed
CN-101061179-B Flame retardant thermoplastic resin composition CHEIL IND INC 2012-07-04 CN disclosed
US-8119726-B2 polycarbonate resin, a rubber modified vinyl-grafted copolymer, a fluorinated polyolefin( PTFE) a phosphorous mixture of a cyclic phosphazene oligomer compound and a phosphate ester morpholide compound or a phosphoric acid ester as a flame retardant CHEIL INDUSTRIES INC. (KR) 2012-02-21 US disclosed
EP-1799766-B1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2010-03-17 EP disclosed
US-7511088-B2 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2009-03-31 US disclosed
EP-1534781-B1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2008-09-24 EP disclosed
US-20070295946-A1 Flame Retardant Thermoplastic Resin Composition CHEIL INDUSTRIES INC. (KR) 2007-12-27 US disclosed
EP-1799766-A4 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2007-10-31 EP disclosed
CN-101061179-A Flame retardant thermoplastic resin composition CHEIL IND INC (KR) 2007-10-24 CN disclosed
EP-1799766-A1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION Cheil Industries Inc. (KR) 2007-06-27 EP disclosed
WO-2006041237-A1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL INDUSTRIES INC. (KR) 2006-04-20 WO disclosed
US-20050245648-A1 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC (KR) 2005-11-03 US disclosed
EP-1534781-A4 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2005-10-26 EP disclosed
EP-1534781-A1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION Cheil Industries Inc. (KR) 2005-06-01 EP disclosed
WO-2004007611-A1 FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITION CHEIL INDUSTRIES INC. (KR) 2004-01-22 WO disclosed