Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.62 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24199997 | 1.00 | GRIK1 (0.62) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| Alcohol SCHEMBL31415589 | 0.96 | GRIK1 (0.59) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| Alcohol SCHEMBL31415577 | 0.96 | GRIK1 (0.59) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL15209530 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL265335 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL7901772 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL7901906 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL15209173 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL15208712 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 | |
| SCHEMBL15208444 | 0.96 | CPB2 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272783-A1 | Amino acids with affinity for the alpha2delta-protein | BARTA NANCY SUE | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272783-A1 | Amino acids with affinity for the alpha2delta-protein | SCN2A, OPRD1, SCN1A | GRIK1 507/4885GRIK2 181/4885SLC1A2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.