Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419959 | 0.91 | TSHR (0.51) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL6418115 | 0.90 | CES2 (0.47) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL6415141 | 0.87 | CES2 (0.55) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL6411619 | 0.81 | TSHR (0.50) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL6410973 | 0.76 | TSHR (0.51) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL19388239 | 0.76 | CES2 (0.57) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL8310773 | 0.74 | CES2 (0.72) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL14782239 | 0.74 | CES2 (0.55) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL5050004 | 0.73 | TSHR (0.51) | CES2CES1RAB9AALDH1A1NPC1 | |
| SCHEMBL5875594 | 0.72 | HSPA5 (0.49) | CES2CES1RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | WADA KATSUAKI (JP) | 2005-03-03 | — | — | US | disclosed |
| US-6593358-B1 | Method for controlling pests, comprising the step of allowing a pesticidally effective amount of one or more compounds selected from the group consisting of one or more compounds of the formula (Ia) according to claim 2 and one or compounds | NIHON BAYER AGROCHEM K.K. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1200425-A1 | THIENYL-PYRAZOLES AND THEIR USE FOR CONTROLLING PESTS | NIHON BAYER AGROCHEM K.K. (JP) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005787-A1 | THIENYL-PYRAZOLES AND THEIR USE FOR CONTROLLING PESTS | NIHON BAYER AGROCHEM K.K. (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050048092-A1 | Thienyl-pyrazoles and their use for controlling pests | CBR3, C1S, CYP4B1 | CES2 840/4885CES1 413/4885RAB9A 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.