Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 9/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6416377 | 0.99 | CCR2 (0.53) | CCR2CCR5OPRM1OPRL1 | |
| SCHEMBL6417586 | 0.92 | CCR2 (0.65) | CCR2CCR5 | |
| Hydrochloric Acid SCHEMBL6409287 | 0.91 | CCR2 (0.64) | CCR2CCR5 | |
| SCHEMBL6411146 | 0.89 | CCR2 (0.56) | CCR2CCR5OPRM1OPRL1 | |
| SCHEMBL6415517 | 0.89 | CCR2 (0.56) | CCR2CCR5OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL6410062 | 0.88 | CCR2 (0.55) | CCR2CCR5OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL6410141 | 0.88 | CCR2 (0.55) | CCR2CCR5OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL6408966 | 0.88 | CCR2 (0.55) | CCR2CCR5OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL6413370 | 0.88 | CCR2 (0.55) | CCR2CCR5OPRM1OPRL1 | |
| SCHEMBL6415563 | 0.87 | HSD11B1 (0.45) | CCR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA INC (CA) | 2005-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | CXCR1, CXCR4, CXCR2 | CCR2 5/4885CCR5 4/4885OPRM1 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.