Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10962051 | 0.72 | ACMSD (0.49) | ACMSDALDH1A1 | |
| Bicarbonate SCHEMBL2907611 | 0.72 | ACMSD (0.49) | ACMSDALDH1A1 | |
| Bicarbonate SCHEMBL10441915 | 0.72 | ACMSD (0.49) | ACMSDALDH1A1 | |
| SCHEMBL593023 | 0.72 | MEN1 (0.65) | KMT2AMEN1POLBRAB9ARPS6KB2 | |
| SCHEMBL29803676 | 0.72 | L3MBTL1 (0.44) | KMT2AMEN1POLBRAB9AGLA | |
| SCHEMBL9734047 | 0.70 | TYMP (0.37) | KMT2AMEN1ACMSDALDH1A1 | |
| SCHEMBL2615881 | 0.70 | MEN1 (0.63) | KMT2AMEN1POLBRAB9ARPS6KB2 | |
| SCHEMBL2615879 | 0.70 | MEN1 (0.63) | KMT2AMEN1POLBRAB9ARPS6KB2 | |
| Hydrochloric Acid SCHEMBL9447525 | 0.70 | MEN1 (0.63) | KMT2AMEN1POLBRAB9ARPS6KB2 | |
| Hydrochloric Acid SCHEMBL9447603 | 0.68 | MEN1 (0.61) | KMT2AMEN1POLBRAB9ARPS6KB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209284-A1 | Tec kinase inhibitors | TEC, ITK, TXK | KMT2A 1803/4885MEN1 3793/4885POLB 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.