Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.36 |
| ▸ | G6PD | P11413 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | USP8 | P40818 | 2/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410254 | 0.95 | NSD2 (0.36) | NSD2G6PDDNMT1ADORA2AADORA1 | |
| SCHEMBL6407781 | 0.80 | S100A4 (0.50) | NSD2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6408454 | 0.78 | NSD2 (0.40) | NSD2G6PDDNMT1ADORA2AADORA1 | |
| SCHEMBL6410278 | 0.74 | MAPT (0.36) | G6PDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6415723 | 0.74 | S100A4 (0.50) | NSD2KMT2AMEN1TDP1BLM | |
| SCHEMBL6408521 | 0.73 | LMNA (0.42) | MAPTKMT2AKDM4ETDP1MAOA | |
| SCHEMBL6414247 | 0.73 | MAPT (0.37) | G6PDMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6413377 | 0.72 | NSD2 (0.40) | NSD2G6PDDNMT1MAPTKMT2A | |
| SCHEMBL6410373 | 0.71 | MAPT (0.36) | G6PDMAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL6407769 | 0.70 | LMNA (0.44) | MAPTKMT2AKDM4ETDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202993-B1 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LAFON LABOR (FR) | 2005-10-19 | — | — | EP | disclosed |
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |
| EP-1202993-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001012632-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | disclosed |