Anisole

Anisole

SCHEMBL641376

COc1ccccc1.Cl[Al](Cl)Cl

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.78
LTA4H P09960 3/20 0.64
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
TRPA1 O75762 1/20 0.50
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44
ACHE P22303 2/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 2/20 0.42
PKM P14618 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL20328417 0.88
Anisole SCHEMBL1205 0.88
Anisole SCHEMBL30601749 0.88
Anisole SCHEMBL8472521 0.88 CA4 (1.00) CA4LTA4HCA12CA1CA2
Anisole SCHEMBL10721106 0.88 CA4 (1.00) CA4LTA4HCA12CA1CA2
Anisole SCHEMBL2493788 0.88 CA4 (1.00) CA4LTA4HCA12CA1CA2
Anisole SCHEMBL28813915 0.88 CA4 (1.00) CA4LTA4HCA12CA1CA2
Anisole SCHEMBL3630332 0.86 CA4 (0.82) CA4LTA4HCA12CA1CA2
Anisole SCHEMBL2336805 0.85
Anisole SCHEMBL5377903 0.85 CA4 (0.93) CA4LTA4HCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007122628-A1 IMPROVED PROCESS FOR PREPARATION OF HIGHLY PURE CEFOTETAN DISODIUM LUPIN LIMITED (IN) 2007-11-01 WO claimed
CN-105481848-A Cefotetan active ester and high purity cefotetan acid preparation method CHONGQINGG TIANDI PHARMACEUTICAL CO LTD CHINA 2016-04-13 CN disclosed
CN-103524449-B Method for synthesizing 2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide SHANDONG BOYUAN PHARMACEUTICAL CO LTD 2015-06-03 CN disclosed
CN-103524449-A Method for synthesizing 2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide SHANDONG BOYUAN PHARMACEUTICAL CO LTD 2014-01-22 CN disclosed
US-8541573-B2 Substituted sulfonamide compounds GRUENENTHAL GMBH (DE) 2013-09-24 US disclosed
US-8318769-B2 Substituted sulfonamide compounds GRUENETHAL GMBH (DE) 2012-11-27 US disclosed
CN-102718780-A Preparation method of cefmetazole sodium WEINA LIU 2012-10-10 CN disclosed
US-8268814-B2 Substituted sulfonamide compounds GRUENENTHAL GMBH (DE) 2012-09-18 US disclosed
US-8263598-B2 Substituted sulfonamide compounds GRUENENTHAL GMBH (DE) 2012-09-11 US disclosed
US-8178535-B2 Substituted sulfonamide compounds having bradykinin 1 receptor activity and use thereof as medicaments GRUENENTHAL GMBH (DE) 2012-05-15 US disclosed
WO-2009090054-A1 SUBSTITUTED SULFONAMIDE DERIVATIVES Grünenthal GmbH (DE) 2009-07-23 WO disclosed
WO-2009090055-A1 SUBSTITUTED SULFONAMIDE DERIVATIVES Grünenthal GmbH (DE) 2009-07-23 WO disclosed
US-20070293482-A1 Process for Preparing Benzodiazepines NOVARTIS PHARMACEUTICALS CORPORATION (US) 2007-12-20 US disclosed
WO-2007122628-A1 IMPROVED PROCESS FOR PREPARATION OF HIGHLY PURE CEFOTETAN DISODIUM LUPIN LIMITED (IN) 2007-11-01 WO disclosed
WO-2007122628-A1 IMPROVED PROCESS FOR PREPARATION OF HIGHLY PURE CEFOTETAN DISODIUM LUPIN LIMITED (IN) 2007-11-01 WO disclosed
WO-2005090319-A1 PROCESS FOR PREPARING BENZODIAZEPINES ARROW THERAPEUTICS LIMITED (GB) 2005-09-29 WO disclosed
EP-0321187-B1 6-(SUBSTITUTED METHYLENE)PENEMS BEECHAM GROUP PLC (GB) 1993-07-28 EP disclosed
WO-1993003042-A1 6-ETHYLIDENE PENEM DERIVATIVES SMITHKLINE BEECHAM PLC (GB) 1993-02-18 WO disclosed
US-4931434-A Penem compounds BEECHAM GROUP P.L.C. (GB) 1990-06-05 US disclosed
EP-0321187-A1 6-(Substituted methylene)penems BEECHAM GROUP PLC (GB) 1989-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293482-A1 Process for Preparing Benzodiazepines CNR1, SIGMAR1, GABRA3 CA4 1114/4885LTA4H 2915/4885CA12 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.