Phosphoric Acid

Phosphoric Acid

SCHEMBL64139

NCCO.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.61

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB3 known ✓ P13945 1/20 0.41
ALDH1A1 P00352 2/20 0.61
TSHR P16473 2/20 0.61
LMNA P02545 3/20 0.45
BLM P54132 2/20 0.45
CYP3A4 P08684 1/20 0.45
NFKB1 P19838 1/20 0.45
PMP22 Q01453 1/20 0.45
GABBR2 O75899 5/20 0.41
GABBR1 Q9UBS5 5/20 0.41
FDPS P14324 3/20 0.41
PDE3A Q14432 2/20 0.41
PDE4D Q08499 1/20 0.41
CYP1A2 P05177 1/20 0.41
THPO P40225 1/20 0.41
ANPEP P15144 1/20 0.38
ERAP2 Q6P179 1/20 0.38
OTC P00480 1/20 0.38
GABRR1 P24046 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL1831539 1.00 ALDH1A1 (0.61) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL1832300 1.00 ALDH1A1 (0.61) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL63996 1.00
Phosphoric Acid SCHEMBL27808770 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL18700978 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL5062015 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL29008723 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL27765121 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL5652669 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4
Phosphoric Acid SCHEMBL27526074 0.96 ALDH1A1 (0.57) ALDH1A1TSHRLMNABLMCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023027178-A1 METHOD FOR PRODUCING CYTIDINE-5'-DIPHOSPHATE COMPOUND 協和発酵バイオ株式会社 2023-03-02 WO claimed
WO-2023026449-A1 METHOD FOR PRODUCING CYTIDINE 5'-DIPHOSPHATE COMPOUND 協和発酵バイオ株式会社 2023-03-02 WO claimed
US-8337863-B2 Anti-sepsis conjugate vaccine ENDOBIOLOGICS, INCORPORATED (US) 2012-12-25 US claimed
US-20120301500-A1 ANTI-SEPSIS CONJUGATE VACCINE ENDOBIOLOGICS, INCORPORATED (US) 2012-11-29 US claimed
US-8128942-B2 Anti-sepsis conjugate vaccine ENDOBIOLOGICS, INCORPORATED (US) 2012-03-06 US claimed
WO-2007059115-A1 ANTI-SEPSIS CONJUGATE VACCINE ENDOBIOLOGICS, INCORPORATED (US) 2007-05-24 WO claimed
US-20060073163-A1 Anti-sepsis conjugate vaccine ENDOBIOLOGICS, INCORPORATED. 2006-04-06 US claimed
US-20030138448-A1 Anti-sepsis conjugate vaccine GUSTAFSON, GARY L. 2003-07-24 US claimed
EP-1278548-A2 LIPOPOLYSACCHARIDE-CONJUGATE VACCINE FOR SEPSIS TREATMENT ENDOBIOLOGICS, INCORPORATED (US) 2003-01-29 EP claimed
WO-2001078787-A2 LIPOPOLYSACCHARIDE-CONJUGATE VACCINE FOR SEPSIS TREATMENT ENDOBIOLOGICS, INCORPORATED (US) 2001-10-25 WO claimed
CN-116249720-B Detoxified Lipopolysaccharide (LPS), natural non-toxic LPS and its use 赫菲斯托斯制药公司 2024-12-03 CN disclosed
CN-116249720-A Detoxified Lipopolysaccharide (LPS), natural non-toxic LPS and its use 赫菲斯托斯制药公司 2023-06-09 CN disclosed
WO-2023026449-A1 METHOD FOR PRODUCING CYTIDINE 5'-DIPHOSPHATE COMPOUND 協和発酵バイオ株式会社 2023-03-02 WO disclosed
WO-2023027178-A1 METHOD FOR PRODUCING CYTIDINE-5'-DIPHOSPHATE COMPOUND 協和発酵バイオ株式会社 2023-03-02 WO disclosed
CN-105683130-B Curing accelerator comprising ettringite and calcium silicate hydrate 巴斯夫建筑方案股份有限公司 2018-03-23 CN disclosed
US-8337863-B2 Anti-sepsis conjugate vaccine ENDOBIOLOGICS, INCORPORATED (US) 2012-12-25 US disclosed