Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414157 | 1.00 | MET (0.48) | METMAPTPOLBTP53SMN1; SMN2 | |
| SCHEMBL6503291 | 0.86 | MET (0.52) | METMAPTPOLBTP53SMN1; SMN2 | |
| SCHEMBL6506319 | 0.86 | MET (0.52) | METMAPTPOLBTP53SMN1; SMN2 | |
| SCHEMBL6507458 | 0.82 | BIRC5 (0.67) | METMAPTPOLBTP53SMN1; SMN2 | |
| SCHEMBL6507461 | 0.82 | BIRC5 (0.67) | METMAPTPOLBTP53SMN1; SMN2 | |
| SCHEMBL6438176 | 0.79 | MAPT (0.51) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6438174 | 0.79 | MAPT (0.51) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6415154 | 0.78 | MAPT (0.49) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6415150 | 0.78 | MAPT (0.49) | MAPTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6436712 | 0.77 | MAPT (0.57) | MAPTPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |