SCHEMBL6414482

SCHEMBL6414482

[CH2]C(c1cccc2ccccc12)[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.48
RXRA P19793 1/20 0.43
CYP3A4 P08684 1/20 0.41
TSHR P16473 2/20 0.41
HPRT1 P00492 1/20 0.40
ACP3 P15309 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
HNF4A P41235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5254081 0.80 TSHR (0.57) ALDH1A1CYP3A4TSHRHPRT1TDP1
SCHEMBL5690907 0.78 ALDH1A1 (0.55) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL5690911 0.77 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL5691918 0.77 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL265334 0.77 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL5691915 0.77 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL3255966 0.77 ALDH1A1 (0.62) ALDH1A1CYP2C9CYP2C19CYP1A2CYP3A4
SCHEMBL6263860 0.77 ALDH1A1 (0.46) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL5752626 0.73 ALDH1A1 (0.46) ALDH1A1CYP2C9CYP2C19CYP1A2RXRA
SCHEMBL7459660 0.72 ALDH1A1 (0.52) ALDH1A1CYP2C9CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1180765-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS INC (JP) 2005-04-06 EP disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 EP disclosed
CN-1133838-A Improved process for alkylation with triazoles ROHM & HAAS (US) 1996-10-23 CN disclosed