Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690907 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL5690911 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL5691918 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL6414482 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL5691915 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL11523492 | 0.76 | CYP1A2 (0.39) | ALDH1A1CYP1A2TSHRLMNACYP3A4 | |
| SCHEMBL5623819 | 0.76 | ADRB2 (0.41) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL27548 | 0.75 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL20560402 | 0.75 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL6286423 | 0.75 | KIF11 (0.47) | ALDH1A1CYP1A2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655070-B1 | OXIDATION CATALYST | ASAHI KASEI CHEMICALS CORP (JP) | 2015-07-15 | — | — | EP | disclosed |
| US-8133834-B2 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| CN-1835800-B | Oxidation catalyst | ASAHI CHEMICAL CORP (JP) | 2010-04-28 | — | — | CN | disclosed |
| US-20100069670-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| WO-2009038411-A2 | BETA-SECRETASE INHIBITING COMPOUNDS HAVING OXO-DIHYDRO-PYRAZOLE MOIETY | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |
| US-20060229471-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2006-10-12 | — | — | US | disclosed |
| CN-1835800-A | Oxidation catalyst | ASAHI CHEMICAL CORP (JP) | 2006-09-20 | — | — | CN | disclosed |
| EP-1655070-A1 | OXIDATION CATALYST | Asahi Kasei Chemicals Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069670-A1 | Oxidation catalyst | PPOX, SOD1, HAO2 | ALDH1A1 377/4885CYP1A2 131/4885CYP2C9 408/4885 |
| US-20060229471-A1 | Oxidation catalyst | PPOX, SOD1, HAO2 | ALDH1A1 377/4885CYP1A2 131/4885CYP2C9 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.