Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 2/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110545 | 0.90 | PIM1 (0.54) | FLT3MAOBPIM1SLC6A2SLC6A4 | |
| SCHEMBL6414486 | 0.88 | FLT3 (0.43) | IKBKETBK1FLT3MAOBPIM1 | |
| SCHEMBL6110933 | 0.86 | FLT3 (0.44) | IKBKETBK1FLT3MAOBPIM1 | |
| SCHEMBL6415969 | 0.81 | PARP10 (0.47) | IKBKETBK1FLT3PARP10 | |
| SCHEMBL6414483 | 0.79 | MAOB (0.56) | MAOBPIM1HRH3ACSL1ACSL3 | |
| SCHEMBL25636954 | 0.77 | KDM4E (0.52) | FLT3MAOBPIM1PARP10SLC6A2 | |
| SCHEMBL14785106 | 0.77 | HPGD (0.46) | IKBKETBK1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL443026 | 0.74 | HPGD (0.50) | HRH3RAB9A | |
| SCHEMBL5806070 | 0.74 | TAS1R3 (0.62) | FLT3TAS1R3TAS1R1 | |
| SCHEMBL3012096 | 0.74 | PARP10 (0.73) | PARP10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |