Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.37 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110545 | 0.88 | PIM1 (0.54) | FLT3MAOBPIM1SLC6A2SLC6A4 | |
| SCHEMBL6414487 | 0.88 | IKBKE (0.48) | FLT3MAOBPIM1SLC6A2SLC6A4 | |
| SCHEMBL6110933 | 0.85 | FLT3 (0.44) | FLT3MAOBPIM1SLC6A2SLC6A4 | |
| SCHEMBL6415966 | 0.81 | S1PR1 (0.44) | FLT3PIM1SLC6A2SLC6A4ACACB | |
| SCHEMBL6414483 | 0.78 | MAOB (0.56) | MAOBPIM1HRH3ACSL1ACSL3 | |
| SCHEMBL25636954 | 0.76 | KDM4E (0.52) | FLT3MAOBPIM1SLC6A2SLC6A4 | |
| SCHEMBL5806063 | 0.75 | TAS1R3 (0.60) | FLT3TAS1R3TAS1R1 | |
| SCHEMBL14785106 | 0.74 | HPGD (0.46) | IKBKETBK1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL6419774 | 0.73 | KAT2B (0.45) | TBK1ACSL1ACSL3ACSL6 | |
| SCHEMBL443026 | 0.73 | HPGD (0.50) | HRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |