Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6414722 | 0.99 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6417350 | 0.92 | DRD2 (0.36) | POLBALDH1A1DRD2EGLN1 | |
| Hydrochloric Acid SCHEMBL6417345 | 0.91 | DRD2 (0.36) | ALDH1A1OPRD1DRD2EGLN1 | |
| SCHEMBL6409117 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1MMP1 | |
| Hydrochloric Acid SCHEMBL6408867 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1MMP1 | |
| Hydrochloric Acid SCHEMBL6411257 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MMP1MMP9MMP13 | |
| Hydrochloric Acid SCHEMBL6409342 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6411851 | 0.87 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6414737 | 0.87 | CCR5 (0.41) | MEN1KMT2APOLBALDH1A1MMP1 | |
| SCHEMBL6410779 | 0.87 | KMT2A (0.42) | MEN1KMT2APOLBALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA INC (CA) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | CXCR1, CXCR4, CXCR2 | SMN1; SMN2 4429/4885MEN1 4007/4885KMT2A 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.