Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 6/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204921 | 0.84 | EIF4E (0.43) | MEN1KMT2AMAPTKDM4EEIF4E | |
| SCHEMBL996247 | 0.80 | TSHR (0.45) | MEN1KMT2AMAPTKDM4EEIF4E | |
| Bromide SCHEMBL468140 | 0.79 | MAPT (0.38) | MEN1KMT2AMAPTKDM4EEIF4E | |
| SCHEMBL6224446 | 0.76 | TYR (0.40) | MAPTKDM4EPOLBSHMT1SHMT2 | |
| SCHEMBL995982 | 0.73 | EIF4E (0.43) | MEN1KMT2AMAPTKDM4EEIF4E | |
| SCHEMBL4469426 | 0.71 | TSHR (0.44) | MEN1KMT2AMAPTKDM4EEIF4E | |
| SCHEMBL27306341 | 0.70 | RAB9A (0.57) | MEN1KMT2AMAPTKDM4EESR2 | |
| SCHEMBL4953327 | 0.70 | BACE1 (0.50) | BACE1ESR1ESR2POLBEGFR | |
| Bromide SCHEMBL9271730 | 0.69 | RAB9A (0.55) | MEN1KMT2AMAPTKDM4EESR2 | |
| SCHEMBL27835698 | 0.68 | GAA (0.44) | MAPTEIF4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277676-A1 | M3muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277676-A1 | M3muscarinic acetylcholine receptor antagonists | CHRM3, CHRM2, CHRM5 | MEN1 2024/4885KMT2A 2289/4885PSMD14 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.